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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37d70758a26516f4efa0796572cfd6273d9ad0f9622c452d2c17dee80f7f62e2' 
  AND token = 'IlSHb9EsX0Y05n+gISGAZLbdkThbOQ3eVqIxnWx0Rc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}