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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '574e384136ca0402b0899dd5ee32fffb017f2b152b31dfacf6f1b46f8382e008' 
  AND token = 'R2OsVbqdnAIFT/JYHLsaRjmU8ZpiAfholbd4N5LNAAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}