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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c5ebe335e2d581bfcad40c337213c16d117e05f3778343025fd4fb2fbdc0fdd' 
  AND token = 'sEEGSd2ccBsEM+ErOOzCtBDVh3jCyB+GiQ8L2GS/LQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}