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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5269d7a323918654407d6857aec341440d32bd2166f5de5099914cbfce4cd4be' 
  AND token = 'eDLuVmDQLVyJkyUqn0x0MjdVZnDAMTz4anFSNrcGhnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}