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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a181013c8b316939c6fb8d0a2d08048652202091fff7a942bbddb9ed63fb53' 
  AND token = 'dTS9IRu2gqbw0k4bsBSrkSxm1p2FmoGoXHRKib3XsA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}