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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e639925706b1650c7829b2c4b7bfc86cdb3e4c33f70c423c572d4d8544a7c9fd' 
  AND token = '3mMzDPhedJ85bMtlSO0RIz+pdOIKtCQYJysZ36jgV0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}