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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '818678bfbaa9c5dc705c5a056f1094cfdfc8d8883360cbb2636e16bd5906d3a4' 
  AND token = 'qr8iPfWdbv+CCDQVI/D/VZ07Ty1+TD6nRA9z3qSikAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}