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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cd4c191b423787a09061b1b73c1da20131607ffd08450ac0e23f770995a4c9a' 
  AND token = 'rf2YLj2OmuoRHIwEkxBwmkAeDx0/jnWS3xDT4JdDKm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}