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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f388afd606b1a9d34e03dbfc9836f303b63daf66f39c283c99c2587a74a736f' 
  AND token = '7V9Kk7WmChs6EA8yXqDUlZQ08ZZzvOjDjOsGcZuy9vI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}