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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ffc1741a085e1a9706e6e8512dcf42f6993a757b056f167e24adc0f9e1cc503' 
  AND token = '3HWPYUdmDoMKTWdaIXAOz7FxNZeUYLgVJgQs/pEN9WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}