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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '084b43625f17b729f02bd12cb7ac5fcd02b82bd9319701fa7de6606e19f43e87' 
  AND token = '3mMKKF4DrxSPS30+XzC/tDA+SNoEa9cPgxvO4h4DRtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}