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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e05609552476d87469a27dda93b0c37774683ba10f4a3e9bc7f6ddf1d425a2' 
  AND token = 'gKGduBSjEX1zM41VtjwHxBgo4W/NT72AdjGYnnaknao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}