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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb0510454aea2fc0f84949a9b8ec32f0a56c3b6eecf36deb2116a6f5c9df2b6' 
  AND token = 'DV0PMHe5bJZ/qL+1mExrUaI9z7M0X3UXavZyifeo3Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}