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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e9b0ac3463b95c285f31e67ba25cc3c31abbec34da1a7ef7146dbc303a23ef0' 
  AND token = '6tTp8IhO3lgPsOXg+ZE4Dq/CosBktBq3JhCLCE0tN5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}