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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80dd5f619b74315f428183232d317a3106ca0819fd1746e02d66a7a5835e2dfa' 
  AND token = '1Og65YDJIEXS1Tybr3FREqqnjm22VqMtYN/PVWPBcOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}