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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '536c2a2647b5e06bde88ae08fa865ba50f458b1f1833a3a4fa48496fed65fc59' 
  AND token = '0jwHoFYoj28qTS7S6fCiT3TwzmPSHc9Xt8m6JJdWWzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}