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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0980a55ef9053823738d8f54e2311f1ac0ca7fd66f4e0369fc15860e740d4d67' 
  AND token = '+BtIMyUrBkll7Fytuzr2cvLOLwfPITifsLZGLpZM/vU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}