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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1cca7e248ad5b08e5558fe4164a4342b3564065a7e8cd4c374e6c7c9febfc0b' 
  AND token = 'HoF3sQWFENmHGKwDVmtrLNAYdhQ7j7F6F0Fnz8mE3VA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}