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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de50d398a9198002e15b0d0a491e6800396a20f632cdd6b569170e8d5a9dc41f' 
  AND token = '3gckbTf5KrOj1XsdchH29SMBSh+meDhFmo1PR8VsLiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}