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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b4c227c4e4c13b30a832edb05560dfeb57d250b86a73011d6fd934a08e2222' 
  AND token = 'i1ysyy3UZ8k71gGF5icBltovJidR+eJSaWdfM+XhUI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}