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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a20a79e052d43093e82c3508869c1f5d8a020bb7ab12cb60c33cb9e94580d51' 
  AND token = 'nyYxbF9T8xZf9UksCxwpUqqeKCXZwT/JwMrqUFccJgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}