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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f494dd7af50e7ec555bab508be72c02ca22a8b4eb8365d1fac54c61ff4797160' 
  AND token = 'D2ItF8qqnBQl1WjyYUq7R4UP2SOB1v+MUL7oSkwGJ6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}