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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e3cea89d62cc294df0a06e4717999c2ff83e5e915a33190bbee572f8991246' 
  AND token = 'uEj6SZqCzX2eIzh/oOovHoe+01tlgBLo+uqaa9Ip3h8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}