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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '602d701bab6838e1b8afbe2fa13a4f35110b964d87b0e98ca96666263522fdb4' 
  AND token = 'n2QwWbSM88ypSc1SYVcvBqpLZK6a/FW86j5mLv5/h3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}