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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57a753c6a9cdf44ee0f7451024c4a9b734d07ee7a55d53932ed16b4ebf1b06d6' 
  AND token = 'IqVyLivPbBLEDV2WJWdHCS2UFCKoBm+7/WjtwP+SKk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}