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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d2ca809e5d92617b9256fc4489dba17d04637713237a35cda86df61a232c34' 
  AND token = 'FTsUcNr+eAC/wrYUOPXHyeHR/kYMi9OiHBYr19iFQYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}