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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21737f30b82f6076bc00200c2001345d66b0fe6e6fd47986e7d4f6437c0658d4' 
  AND token = '0ES368MR/U989zuNlQjqKTm6sRwZiltOuiYF4MB8OMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}