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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c43e942abee866e7dc4ac17a7bd8f1606a89def6f81c308c85843420f334234' 
  AND token = '8mliF5TjZ7t3XW4h1Py9OuCQJHp0LWlGJM0BwWxxtm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}