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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59fb7d544701786274706b7eb02ebfab4ddb0869650499b2210f0f83d4a0baf2' 
  AND token = 'zN7M1Q6c3zvOPY8FSwnk58Mp1l9Wm/+tqAqKRGfMqH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}