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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '152d82184408848fe0aee4f84c28adc6c226b3ecb91a7d33d6b6d3cf4fe26abd' 
  AND token = 'bPncuP/PqtDZWaAPQ6PjD/5QDnAvt1TDk6EhzuVGlsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}