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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effd2973a3acb867e30c6e067529ba321c1fd2fb42df28fc84c10aae0d814ec8' 
  AND token = 'r+FZtRhVuianU+i0zXm1ZEdWd/0Ap5wwZpkvdWmabos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}