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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de22682ebabad4704cd32fa97677ded342c75c84e273195f9537edb0b6743978' 
  AND token = '8i8e+9lPMCcSrw33cD5ySaTbtbJP2zVL+xXeh+YzwbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}