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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9bf8a44ae51deded422dd403a010f403a3adb526a0467c127e96169216c7d7' 
  AND token = 'V9jr+afuOEIVtWw5vkRyNzIpUjdFwloZ6c0OGXg7GK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}