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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27a22f1ddea482b6f85c8d334997360f13b172c87e1cc0a3783a27c320bd76f' 
  AND token = '3qZbHpyWo+rhhj483XZ3N83FToBIuRt6+zsFgLZ+Djo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}