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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d077722f5c12155b2bd9da4ee358daf78c74b7a72c4fda031e9c3fe2c607315' 
  AND token = 'bVDyq3MZlTl8HLL7CQd6LbjnGlWemZ3kv8h6PraqC2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}