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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de4c61e438353e0c5c09d5140369d8067428dfdd02e49ea392054a0e2b8b72f6' 
  AND token = '3TX2cgyLmIeV2yIUE+2Ie1BJcHpbkrhWLaUdqwfuWtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}