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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef166e13a14b5b62c7474099733a81104f38b09d0028902c43d6c8de8218824c' 
  AND token = '6irqtLKm1vbpJd9fSqMhZH12+H2HaZbnDnQwb2ZFPy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}