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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fd598f53666b62847945b957a6f61e833f89a61b2e0d34fc9b02acff450c0d' 
  AND token = 'UFEZpMyRIIk0P4ZsEpezjgRy+KTkegXfY1ECjUyqZaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}