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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2e091e7fa5500699f9fb3f90305e2a0f9538289bf53c00206ea72f67fd1c485' 
  AND token = 'WeEswSt4t+ect9WKnLzoWQWB2tKYUbOD5M1DbC/rf/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}