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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cea5c9bf5da10f1397c40f012e2c1b58be65e520074c2272e4fad8f4f5a0179f' 
  AND token = 'Sz29YcjxnxEolHd9iYdOWm59bhG1zLVmUcdHT3tzpXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}