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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dddc8c242508dc0dfec46f66ca022f191643c51f1e76b35b6998b9b598c59dcf' 
  AND token = 'uznWSXnqEDZrW6u1e2pg/a2dBPK8SMjc4jp0iazTk98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}