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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd527a63f35f7ed4484b06d6a9190050a97d644fec7452a2627c0ab1c8003dce4' 
  AND token = 'QsA2PBpaOjHLsuAkNpjiDgN20RJ8+XrJhXbmf+LZKV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}