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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b80b76927a4f9fc7331f1a4c79beb83ad4ae1f85741123c3b257d2893f4550' 
  AND token = 'JeELSkzaWipsOJjGqDEL8kTKhU4Tcc1+Hyo2k6OFMEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}