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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd525c42de83faf2c59d0bc78340845bec0067be859e9c97d43bca6c2cadcf003' 
  AND token = 'hQji/NWoWAzczvHB99Da+Fy3g+5bL1egq+SUqjLjkdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}