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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f5f58874f4a47a1b0020860336b85f81b6051bd3ac57a4f194ed3f04f12c586' 
  AND token = 'JYMI/nk6JWLw4ehHt5HPeNeA+Q/mk8AB0QLLKCedeBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}