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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d81ed89c1e9b97ca3e1be24de6568053659d0b9e66a822f9f3c7eaf93a4bbce' 
  AND token = 'emceksmdqLwv3VBG7DaN9pGG+VbzBI/N9MArJ9NGVEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}