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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6b58cd456c9dbf31997cc32ebe7bb72cb7cf1f21613946e6127c76a4395dab3' 
  AND token = 'OIrrs11wTaxnbp5RHMwcaPcDR+NJtVcNcvCqRTelVzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}