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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491b4c2a76dd9d358630202023160213dad17cf651cbb7f424998c21fb8ad34a' 
  AND token = 'EK0D3dGmMQvLfe4IfAVwzb5CulWlQxcd0zFx2++Grro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}