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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b116ebdaa5a31f7e6f4ae5afacd8f42385a5d50c56aa82e4247b3442d3b594b' 
  AND token = 'DNXj1MqM8oN8JPRNh23vBXMSE1+B0EaFMIWJs2G29MA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}