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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443c73b1a93105430146adb00c36a64124e82b2e2b76b5c686f13a92b5f6a03f' 
  AND token = 'lZQKAW0mKkY0xMgtmuYjSpq8/9CqQxY8VL2xfqXavc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}